Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:activatedBy |
gptkb:caspase-8
gptkb:caspase-9 gptkb:caspase-3 |
| gptkbp:alternativeName |
CASP-7
CMH-1 ICE-LAP3 apoptotic protease Mch3 |
| gptkbp:cleavage |
gptkb:lamin_A
poly(ADP-ribose) polymerase (PARP) |
| gptkbp:discoveredBy |
1996
|
| gptkbp:EC_number |
3.4.22.60
|
| gptkbp:function |
cysteine-aspartic acid protease activity
execution-phase apoptosis |
| https://www.w3.org/2000/01/rdf-schema#label |
caspase-7
|
| gptkbp:inhibitedBy |
gptkb:XIAP
caspase inhibitors |
| gptkbp:locatedIn |
cytosol
|
| gptkbp:locatedOnChromosome |
chromosome 10q25
|
| gptkbp:molecularWeight |
34 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:product |
CASP7 gene
|
| gptkbp:relatedTo |
gptkb:caspase-9
gptkb:caspase-3 caspase-6 |
| gptkbp:structure |
heterotetramer
|
| gptkbp:UniProtID |
P55210
|
| gptkbp:bfsParent |
gptkb:caspase-8
gptkb:caspases gptkb:granzyme_B |
| gptkbp:bfsLayer |
7
|