|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:binds
|
gptkb:Wnt_proteins
|
|
gptkbp:discoveredBy
|
Hsieh et al.
|
|
gptkbp:discoveredIn
|
1999
|
|
gptkbp:downregulatedIn
|
gptkb:neuroblastoma
gptkb:non-small_cell_lung_cancer
gptkb:Wilms_tumor
gptkb:oral_squamous_cell_carcinoma
gptkb:nasopharyngeal_carcinoma
gptkb:leukemia
gptkb:Sertoli-Leydig_cell_tumor
gptkb:cancer
gptkb:medulloblastoma
gptkb:germ_cell_tumor
gptkb:Kaposi's_sarcoma
gptkb:alveolar_rhabdomyosarcoma
gptkb:renal_cell_carcinoma
gptkb:Small_Cell_Lung_Cancer
gptkb:bladder_cancer
gptkb:embryonal_rhabdomyosarcoma
gptkb:endometrial_cancer
gptkb:rhabdomyosarcoma
gptkb:retinoblastoma
gptkb:pheochromocytoma
gptkb:Paget's_disease
gptkb:Ewing_sarcoma
gptkb:myxoid_liposarcoma
gptkb:clear_cell_sarcoma
gptkb:desmoplastic_small_round_cell_tumor
gptkb:extraskeletal_myxoid_chondrosarcoma
gptkb:paraganglioma
gptkb:angiosarcoma
gptkb:glioma
gptkb:choriocarcinoma
gptkb:embryonal_carcinoma
gptkb:seminoma
gptkb:teratoma
gptkb:yolk_sac_tumor
gptkb:testicular_cancer
gptkb:pituitary_adenoma
gptkb:melanoma
colorectal cancer
esophageal cancer
mesothelioma
multiple myeloma
pancreatic cancer
prostate cancer
adrenocortical carcinoma
cholangiocarcinoma
synovial sarcoma
osteosarcoma
hepatocellular carcinoma
pleomorphic liposarcoma
gastric cancer
liposarcoma
epithelioid sarcoma
Merkel cell carcinoma
basal cell carcinoma
malignant peripheral nerve sheath tumor
malignant fibrous histiocytoma
undifferentiated pleomorphic sarcoma
alveolar soft part sarcoma
dedifferentiated liposarcoma
dysgerminoma
fibrosarcoma
granulosa cell tumor
large cell lung cancer
myxofibrosarcoma
salivary gland carcinoma
sebaceous gland carcinoma
spindle cell sarcoma
|
|
gptkbp:encodedBy
|
gptkb:WIF1_gene
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
gptkb:Wnt_inhibitory_factor_1
|
|
gptkbp:function
|
inhibits Wnt signaling pathway
|
|
gptkbp:gene
|
gptkb:WIF1
|
|
gptkbp:locatedOnChromosome
|
12q14
|
|
gptkbp:location
|
extracellular space
|
|
gptkbp:molecularWeight
|
~42 kDa
|
|
gptkbp:organism
|
gptkb:human
gptkb:mouse
|
|
gptkbp:pathway
|
gptkb:Wnt_signaling_pathway
|
|
gptkbp:role
|
gptkb:tumor_suppressor
epigenetically silenced in some cancers
|
|
gptkbp:structure
|
contains WIF domain
|
|
gptkbp:UniProtID
|
gptkb:Q9Y5W5
|
|
gptkbp:bfsParent
|
gptkb:Wnt_pathway
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
WIF-1
|