Statements (108)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Oncology
|
| gptkbp:affects |
gptkb:Skin
internal organs mucous membranes |
| gptkbp:associated_with |
gptkb:HIV/_AIDS
gptkb:Kaposi's_sarcoma-associated_herpesvirus gptkb:social_stigma fatigue weight loss fever swelling night sweats public health concern respiratory issues edema economic burden lymphadenopathy painful lesions gastrointestinal symptoms psychosocial impact bleeding lesions lymphatic obstruction other malignancies |
| gptkbp:caused_by |
gptkb:Human_Herpesvirus_8
gptkb:human_herpesvirus_8 human herpesvirus 8 (HHV-8) |
| gptkbp:characteristic |
purple or brown lesions
may be asymptomatic can affect internal organs can cause pain or discomfort may lead to swelling |
| gptkbp:characterized_by |
purple or brown lesions
extravasation of blood lymphatic involvement vascular tumors |
| gptkbp:clinical_trial |
ongoing research
|
| gptkbp:diagnosis |
imaging studies
varies by type biopsy can be aggressive varies by subtype can be chronic |
| gptkbp:epidemiology |
increased incidence in the 1980s
|
| gptkbp:first_described_by |
gptkb:Moritz_Kaposi
1872 |
| gptkbp:historical_significance |
first cancer linked to a virus
|
| https://www.w3.org/2000/01/rdf-schema#label |
Kaposi's sarcoma
|
| gptkbp:is_common_in |
older adults
HIV-positive individuals organ transplant recipients endemic populations in Africa individuals with weakened immune systems |
| gptkbp:is_located_in |
gptkb:Skin
lungs gastrointestinal tract lymph nodes mouth |
| gptkbp:named_after |
gptkb:Moritz_Kaposi
|
| gptkbp:prevalence |
more common in men
higher in sub-Saharan Africa higher in immunocompromised individuals more common in certain geographic regions associated with certain ethnicities common in Mediterranean countries higher in men increased in HIV-positive individuals |
| gptkbp:research_focus |
immune response
genetic factors treatment efficacy epidemiology viral pathogenesis |
| gptkbp:risk_factor |
gptkb:region
age African descent gender Mediterranean descent male gender immunosuppression transplant recipients older age certain ethnic backgrounds |
| gptkbp:symptoms |
pain
swelling lesions |
| gptkbp:treatment |
gptkb:immunotherapy
gptkb:surgery supportive care radiation therapy chemotherapy targeted therapy pain management laser therapy cryotherapy |
| gptkbp:type |
gptkb:classic_Kaposi's_sarcoma
gptkb:endemic_Kaposi's_sarcoma vascular tumor epidemic Kaposi's sarcoma iatrogenic Kaposi's sarcoma |
| gptkbp:type_of |
gptkb:classic_Kaposi's_sarcoma
gptkb:endemic_Kaposi's_sarcoma epidemic Kaposi's sarcoma iatrogenic Kaposi's sarcoma |
| gptkbp:variant |
gptkb:classic_Kaposi's_sarcoma
gptkb:endemic_Kaposi's_sarcoma epidemic Kaposi's sarcoma iatrogenic Kaposi's sarcoma |
| gptkbp:bfsParent |
gptkb:National_Institutes_of_Health
|
| gptkbp:bfsLayer |
3
|