|
gptkbp:instanceOf
|
gptkb:cancer
gptkb:disease
gptkb:rare_disease
|
|
gptkbp:affects
|
gptkb:bone
soft tissue
|
|
gptkbp:firstDescribed
|
gptkb:James_Ewing
1921
|
|
gptkbp:hasCharacteristicTranslocation
|
gptkb:t(11;22)(q24;q12)
|
|
gptkbp:hasDiagnosticMethod
|
gptkb:X-rays
gptkb:CT_scan
MRI
biopsy
molecular genetic testing
|
|
gptkbp:hasGeneticAlteration
|
gptkb:EWSR1-FLI1_fusion_gene
|
|
gptkbp:hasMetastasisSite
|
lungs
bone marrow
other bones
|
|
gptkbp:hasOrphanetID
|
284
|
|
gptkbp:hasParentDisease
|
gptkb:rhabdomyosarcoma
bone cancer
|
|
gptkbp:hasSurvivalRate
|
about 30% (metastatic disease)
about 70% (localized disease)
|
|
gptkbp:hasTumorMarker
|
gptkb:CD99
gptkb:FLI1
|
|
gptkbp:hasTypicalOnsetAge
|
childhood
adolescence
|
|
gptkbp:histology
|
small round blue cells
|
|
gptkbp:ICD-10_code
|
C40
C41
|
|
gptkbp:isMoreCommonIn
|
gptkb:Caucasians
males
|
|
gptkbp:isMostCommonIn
|
young adults
teenagers
|
|
gptkbp:location
|
gptkb:meat
gptkb:humerus
femur
pelvis
tibia
|
|
gptkbp:OMIM
|
612219
|
|
gptkbp:prevalence
|
about 3 cases per million per year
|
|
gptkbp:prognosis
|
variable
|
|
gptkbp:rareIn
|
gptkb:African_populations
adults over 30
|
|
gptkbp:riskFactor
|
gptkb:genetic_disorder
|
|
gptkbp:stageName
|
gptkb:AJCC_system
gptkb:Enneking_system
|
|
gptkbp:symptom
|
fever
pain
fatigue
weight loss
swelling
|
|
gptkbp:synonym
|
gptkb:Ewing's_sarcoma
gptkb:Ewing's_tumor
gptkb:Ewing_tumor
|
|
gptkbp:treatment
|
gptkb:radiation_therapy
surgery
chemotherapy
|
|
gptkbp:bfsParent
|
gptkb:Codman’s_triangle
gptkb:Fused_in_Sarcoma
gptkb:STAG2
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Ewing sarcoma
|