embryonal rhabdomyosarcoma

URI: https://gptkb.org/entity/embryonal_rhabdomyosarcoma
GPTKB entity
Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:cancer
gptkb:rhabdomyosarcoma
rhabdomyosarcoma subtype
gptkbp:affects skeletal muscle tissue
gptkbp:canMetastasizeTo lungs
lymph nodes
bone marrow
gptkbp:commonIn children
gptkbp:firstDescribed 1946
gptkbp:histology rhabdomyoblasts
small round blue cells
https://www.w3.org/2000/01/rdf-schema#label embryonal rhabdomyosarcoma
gptkbp:ICD-10_code gptkb:C49
gptkbp:incidence most common soft tissue sarcoma in children
gptkbp:marking gptkb:MyoD1
gptkb:desmin
gptkb:myogenin
gptkbp:medianAge 5 years
gptkbp:mostCommonSite genitourinary tract
head and neck
retroperitoneum
gptkbp:mutationAssociatedWith loss of heterozygosity at 11p15
gptkbp:originatedIn skeletal muscle progenitor cell
gptkbp:prognosis better than alveolar rhabdomyosarcoma
gptkbp:riskFactor gptkb:Li-Fraumeni_syndrome
gptkb:Neurofibromatosis_type_1
gptkb:Beckwith-Wiedemann_syndrome
gptkbp:subspecies gptkb:rhabdomyosarcoma
gptkbp:treatment surgery
radiation therapy
chemotherapy
gptkbp:bfsParent gptkb:chromosome_11p15.5_(HRAS)
gptkb:rhabdomyosarcoma
gptkbp:bfsLayer 5