|
gptkbp:instanceOf
|
gptkb:cancer
brain tumor
|
|
gptkbp:affects
|
adults
children
|
|
gptkbp:canMetastasizeTo
|
gptkb:spinal_cord
cerebrospinal fluid
|
|
gptkbp:cause
|
gptkb:cerebellar_mutism_syndrome
cognitive impairment
endocrine dysfunction
|
|
gptkbp:commonIn
|
children
|
|
gptkbp:diagnosedBy
|
gptkb:CT_scan
MRI
biopsy
|
|
gptkbp:firstDescribed
|
1925
|
|
gptkbp:histology
|
gptkb:Homer_Wright_rosettes
small round blue cells
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
medulloblastoma
|
|
gptkbp:ICD-10_code
|
gptkb:C71.6
|
|
gptkbp:incidence
|
about 500 cases per year in US
|
|
gptkbp:location
|
gptkb:cerebellum
|
|
gptkbp:medianAge
|
6-8 years
|
|
gptkbp:molecularSubtype
|
gptkb:WNT
gptkb:SHH
Group 3
Group 4
|
|
gptkbp:originatedIn
|
gptkb:granule_neuron_precursor
|
|
gptkbp:parentField
|
neuro-oncology
|
|
gptkbp:prognosis
|
variable
depends on molecular subtype
|
|
gptkbp:recurrence
|
possible
often within 2 years if occurs
|
|
gptkbp:riskFactor
|
gptkb:Li-Fraumeni_syndrome
gptkb:Turcot_syndrome
gptkb:Gorlin_syndrome
genetic syndromes
|
|
gptkbp:survivalRate
|
about 70% (children, average risk)
|
|
gptkbp:symptom
|
nausea
vomiting
hydrocephalus
dizziness
headache
ataxia
|
|
gptkbp:treatment
|
surgery
radiation therapy
chemotherapy
|
|
gptkbp:WHOGrade
|
IV
|
|
gptkbp:bfsParent
|
gptkb:brain_tumor
gptkb:Connor_Michalek
|
|
gptkbp:bfsLayer
|
5
|