|
gptkbp:instanceOf
|
gptkb:cancer
gptkb:disease
|
|
gptkbp:affects
|
children
|
|
gptkbp:associatedWith
|
gptkb:ALK
gptkb:PHOX2B
|
|
gptkbp:canBeFamilial
|
yes, rarely
|
|
gptkbp:canMetastasizeTo
|
gptkb:bone
gptkb:skin
liver
lymph nodes
|
|
gptkbp:canRegressSpontaneously
|
yes, in some cases
|
|
gptkbp:cause
|
gptkb:opsoclonus-myoclonus_syndrome
gptkb:paraneoplastic_syndromes
|
|
gptkbp:clinicalTrialPhase
|
gptkb:Children's_Oncology_Group_studies
|
|
gptkbp:diagnosedBy
|
imaging
biopsy
urine catecholamines
|
|
gptkbp:firstDescribed
|
1864
|
|
gptkbp:hasAwarenessMonth
|
September
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
neuroblastoma
|
|
gptkbp:ICD-10_code
|
C74.9
|
|
gptkbp:incidence
|
about 1 in 7,000 live births
|
|
gptkbp:marking
|
N-myc amplification
elevated HVA
elevated VMA
|
|
gptkbp:mortalityRate
|
high in advanced cases
|
|
gptkbp:mostCommonAge
|
<5 years
|
|
gptkbp:mostCommonExtracranialSolidTumorIn
|
children
|
|
gptkbp:originatedIn
|
gptkb:neural_crest_cells
|
|
gptkbp:prognosis
|
variable
|
|
gptkbp:rareIn
|
adults
|
|
gptkbp:riskFactor
|
genetic mutations
|
|
gptkbp:stagedBy
|
gptkb:INRG_system
gptkb:INSS_system
|
|
gptkbp:supportersGroup
|
gptkb:Neuroblastoma_UK
|
|
gptkbp:symptom
|
pain
weight loss
abdominal mass
|
|
gptkbp:treatment
|
surgery
radiation therapy
chemotherapy
stem cell transplant
|
|
gptkbp:website
|
adrenal glands
sympathetic nervous system
|
|
gptkbp:bfsParent
|
gptkb:Robyn_Brooks
|
|
gptkbp:bfsLayer
|
5
|