|
gptkbp:instanceOf
|
gptkb:cancer
|
|
gptkbp:affectsOrgan
|
Lung
|
|
gptkbp:alternativeName
|
small_cell_lung_cancer
|
|
gptkbp:characteristic
|
Early Metastasis
Neuroendocrine Features
Rapid Growth
|
|
gptkbp:class
|
gptkb:World_Health_Organization
|
|
gptkbp:diagnosedBy
|
gptkb:Bronchoscopy
gptkb:PET_Scan
MRI
Imaging
Biopsy
CT Scan
|
|
gptkbp:hasBiomarker
|
gptkb:Chromogranin_A
gptkb:Neuron-Specific_Enolase
gptkb:Synaptophysin
|
|
gptkbp:hasGeneticAlteration
|
MYC Amplification
RB1 Mutation
TP53 Mutation
|
|
gptkbp:hasMedianSurvival
|
16-24 months (Limited Stage)
8-13 months (Extensive Stage)
|
|
gptkbp:hasMetastasisSite
|
gptkb:bone
gptkb:Brain
gptkb:Adrenal_Gland
Liver
|
|
gptkbp:hasParaneoplasticSyndrome
|
gptkb:Cushing_Syndrome
gptkb:Lambert-Eaton_Myasthenic_Syndrome
gptkb:SIADH
|
|
gptkbp:ICD-10_code
|
C34
|
|
gptkbp:incidence
|
About 15% of Lung Cancers
|
|
gptkbp:isMoreCommonIn
|
Males
Older Adults
|
|
gptkbp:prognosis
|
Poor
|
|
gptkbp:rareIn
|
Non-Smokers
|
|
gptkbp:riskFactor
|
gptkb:Asbestos_Exposure
gptkb:Radon_Exposure
gptkb:Secondhand_Smoke
Smoking
|
|
gptkbp:stageName
|
Extensive Stage
Limited Stage
|
|
gptkbp:subspecies
|
gptkb:cancer
gptkb:Combined_Small_Cell_Lung_Cancer
|
|
gptkbp:symptom
|
gptkb:Superior_Vena_Cava_Syndrome
Fatigue
Cough
Hoarseness
Chest Pain
Dysphagia
Hemoptysis
Shortness of Breath
Weight Loss
|
|
gptkbp:synonym
|
gptkb:SCLC
gptkb:Oat_Cell_Carcinoma
|
|
gptkbp:treatment
|
gptkb:Atezolizumab
gptkb:Durvalumab
gptkb:Etoposide
Radiation Therapy
Surgery
immunotherapy
Chemotherapy
Platinum-based Chemotherapy
|
|
gptkbp:bfsParent
|
gptkb:cancer
|
|
gptkbp:bfsLayer
|
4
|