Statements (119)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:vaccine
|
| gptkbp:associated_with |
autoimmune diseases
|
| gptkbp:enhances |
acute phase response
|
| gptkbp:established |
gptkb:adalimumab
gptkb:etanercept apoptosis infliximab |
| gptkbp:function |
inflammatory response
|
| gptkbp:has_role |
cachexia
|
| https://www.w3.org/2000/01/rdf-schema#label |
TNF
|
| gptkbp:influences |
metabolism
cell differentiation cell proliferation angiogenesis |
| gptkbp:interacts_with |
TNF R1
TNF R2 |
| gptkbp:is_aimed_at |
anti-TNF therapies
|
| gptkbp:is_involved_in |
gptkb:musician
gptkb:asthma gptkb:healthcare_organization gptkb:cystic_fibrosis gptkb:sickle_cell_disease gptkb:vitiligo gptkb:Crohn's_disease gptkb:systemic_lupus_erythematosus gptkb:Company gptkb:COVID-19 gptkb:psychologist gptkb:deep_vein_thrombosis gptkb:alopecia_areata gptkb:motorcycle gptkb:computer gptkb:endometriosis gptkb:rheumatoid_arthritis gptkb:systemic_sclerosis gptkb:ankylosing_spondylitis gptkb:psoriatic_arthritis gptkb:reactive_arthritis stroke apoptosis cell differentiation cell proliferation cell signaling hepatitis immune response allergic reactions chronic pain dermatitis inflammation metabolic syndrome obesity urticaria wound healing heart failure neuroinflammation fibrosis cardiovascular diseases seborrheic dermatitis sepsis chronic kidney disease fibromyalgia tumorigenesis cell survival cell death bone resorption eczema immune tolerance insulin resistance psoriasis pulmonary fibrosis acute respiratory distress syndrome thrombosis cancer progression angiogenesis atherosclerosis chronic inflammation anaphylaxis tissue repair cell migration atopic dermatitis transplant rejection chronic obstructive pulmonary disease pulmonary embolism Graves' disease gout muscle wasting periodontitis pericarditis HIV infection joint destruction cancer cachexia chronic inflammatory diseases nephritis thyroiditis lichen planus contact dermatitis autoimmune hepatitis primary biliary cholangitis antiphospholipid syndrome myocarditis septic shock fatigue syndrome cachexia primary sclerosing cholangitis Hashimoto's thyroiditis chronic pelvic pain syndrome interstitial cystitis morphea pityriasis rubra pilaris sclerodermoid changes |
| gptkbp:is_vulnerable_to |
TNF receptor 1
TNF receptor 2 |
| gptkbp:located_in |
chromosome 6
|
| gptkbp:produced_by |
cytokines
macrophages other cytokines |
| gptkbp:regulates |
gptkb:smartphone
|
| gptkbp:bfsParent |
gptkb:Thursday_Night_Football
|
| gptkbp:bfsLayer |
5
|