Crohn's disease

GPTKB entity

Statements (72)
Predicate Object
gptkbp:instance_of gptkb:disease
gptkbp:affects gastrointestinal tract
any part of the gastrointestinal tract
gptkbp:associated_with environmental factors
genetic factors
immune system dysfunction
gptkbp:can_cause gptkb:anemia
joint pain
dehydration
skin problems
vitamin deficiencies
mouth sores
eye inflammation
perianal disease
gptkbp:can_lead_to hospitalization
colon cancer
surgery for complications
gptkbp:cause inflammation
gptkbp:complications malnutrition
intestinal obstruction
fistulas
gptkbp:diagnosis physical examination
endoscopy
medical history
imaging tests
gptkbp:first_described_by gptkb:1932
https://www.w3.org/2000/01/rdf-schema#label Crohn's disease
gptkbp:is_a_chronic_condition gptkb:true
gptkbp:is_associated_with increased risk of blood clots
increased risk of liver disease
increased risk of osteoporosis
gptkbp:is_characterized_by chronic inflammation
skip lesions
gptkbp:is_common_in gptkb:people_of_Ashkenazi_Jewish_descent
young adults
gptkbp:is_less_prevalent_in gptkb:Africa
gptkb:Asia
gptkbp:is_managed_by lifestyle changes
stress management
dietary modifications
gptkbp:is_monitored_by blood tests
imaging studies
regular check-ups
gptkbp:is_often_seen_in gptkb:Europe
gptkb:ulcerative_colitis
gptkb:North_America
gptkbp:named_after gptkb:Burrill_Crohn
gptkbp:prevalence 1.6 million people in the US
gptkbp:scientific_classification a type of inflammatory bowel disease
gptkbp:symptoms fatigue
weight loss
abdominal pain
diarrhea
gptkbp:treatment gptkb:surgery
antibiotics
nutritional support
biologics
corticosteroids
anti-inflammatory drugs
immunosuppressants
clinical trials for new therapies
gptkbp:bfsParent gptkb:Celiac_Disease
gptkb:cyclosporine
gptkb:Humira
gptkb:Stelara
gptkb:Rituximab
gptkb:Remicade
gptkb:Skyrizi
gptkb:interferon-gamma
gptkb:Immunex_Corporation
gptkb:rituximab
gptkbp:bfsLayer 5