|
gptkbp:instanceOf
|
gptkb:drug
gptkb:monoclonal_antibody
|
|
gptkbp:administeredBy
|
intravenous infusion
subcutaneous injection
|
|
gptkbp:approvedBy
|
gptkb:FDA
gptkb:EMA
2009
|
|
gptkbp:ATCCode
|
L04AB06
|
|
gptkbp:CASNumber
|
476181-74-5
|
|
gptkbp:developedBy
|
gptkb:Merck_&_Co.
gptkb:Janssen_Biotech
|
|
gptkbp:hasMolecularFormula
|
C6428H9956N1720O2016S38
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
golimumab
|
|
gptkbp:KEGGID
|
D08913
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:marketedAs
|
gptkb:Simponi_Aria
gptkb:Simponi
|
|
gptkbp:mechanismOfAction
|
TNF inhibitor
|
|
gptkbp:origin
|
gptkb:human
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:product
|
IgG1 kappa monoclonal antibody
|
|
gptkbp:PubChem_CID
|
DB06674
CHEMBL1201836
|
|
gptkbp:routeOfAdministration
|
subcutaneous
intravenous
|
|
gptkbp:sideEffect
|
headache
hypertension
infections
injection site reactions
increased liver enzymes
|
|
gptkbp:target
|
gptkb:tumor_necrosis_factor_alpha
|
|
gptkbp:UNII
|
YJD7J8QW3B
|
|
gptkbp:usedFor
|
gptkb:psoriatic_arthritis
ulcerative colitis
rheumatoid arthritis
ankylosing spondylitis
|
|
gptkbp:bfsParent
|
gptkb:Simponi
|
|
gptkbp:bfsLayer
|
5
|