Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
cytokine
|
| gptkbp:abbreviation |
gptkb:TNF-alpha
|
| gptkbp:alternativeName |
gptkb:tumor_necrosis_factor_alpha
|
| gptkbp:associatedWith |
septic shock
rheumatoid arthritis inflammatory bowel disease |
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
gptkb:TNF_gene
|
| gptkbp:function |
induces fever
regulates immune cells mediates inflammation induces cachexia |
| https://www.w3.org/2000/01/rdf-schema#label |
cachectin
|
| gptkbp:producedBy |
macrophages
|
| gptkbp:recipient |
gptkb:TNFR1
gptkb:TNFR2 |
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:structure |
homotrimer
|
| gptkbp:target |
anti-TNF drugs
|
| gptkbp:bfsParent |
gptkb:tumor_necrosis_factor_alpha
|
| gptkbp:bfsLayer |
6
|