Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
gptkb:monoclonal_antibody |
| gptkbp:administeredBy |
subcutaneous injection
|
| gptkbp:approvedBy |
gptkb:FDA
gptkb:EMA 2008 |
| gptkbp:ATCCode |
L04AB05
|
| gptkbp:brand |
gptkb:Cimzia
|
| gptkbp:CASNumber |
428863-50-7
|
| gptkbp:contraindication |
tuberculosis
active infection |
| gptkbp:developedBy |
gptkb:UCB
|
| gptkbp:drugClass |
gptkb:tumor_necrosis_factor_inhibitor
|
| gptkbp:hasPEGylation |
true
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
TNF inhibitor
|
| gptkbp:molecularWeight |
~91 kDa
|
| gptkbp:pregnancyCategory |
B (US)
|
| gptkbp:routeOfAdministration |
subcutaneous
|
| gptkbp:sideEffect |
nausea
headache injection site reaction rash upper respiratory tract infection |
| gptkbp:UNII |
3X2Q1FCQ6B
|
| gptkbp:usedFor |
gptkb:Crohn's_disease
gptkb:psoriatic_arthritis rheumatoid arthritis ankylosing spondylitis non-radiographic axial spondyloarthritis |
| gptkbp:bfsParent |
gptkb:TNF-alpha
gptkb:TNF |
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
certolizumab pegol
|