|
gptkbp:instanceOf
|
gptkb:drug
gptkb:monoclonal_antibody
|
|
gptkbp:administeredBy
|
subcutaneous injection
|
|
gptkbp:approvedBy
|
gptkb:FDA
gptkb:EMA
2008
|
|
gptkbp:ATCCode
|
L04AB05
|
|
gptkbp:brand
|
gptkb:Cimzia
|
|
gptkbp:CASNumber
|
428863-50-7
|
|
gptkbp:contraindication
|
tuberculosis
active infection
|
|
gptkbp:developedBy
|
gptkb:UCB
|
|
gptkbp:drugClass
|
tumor necrosis factor inhibitor
|
|
gptkbp:hasPEGylation
|
true
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
certolizumab pegol
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
TNF inhibitor
|
|
gptkbp:molecularWeight
|
~91 kDa
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:routeOfAdministration
|
subcutaneous
|
|
gptkbp:sideEffect
|
nausea
headache
injection site reaction
rash
upper respiratory tract infection
|
|
gptkbp:UNII
|
3X2Q1FCQ6B
|
|
gptkbp:usedFor
|
gptkb:Crohn's_disease
gptkb:psoriatic_arthritis
rheumatoid arthritis
ankylosing spondylitis
non-radiographic axial spondyloarthritis
|
|
gptkbp:bfsParent
|
gptkb:TNF-alpha
gptkb:Tnf
gptkb:tumor_necrosis_factor
gptkb:TNF
|
|
gptkbp:bfsLayer
|
7
|