Statements (70)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Cell
|
| gptkbp:can_be_engineered_for |
gptkb:gene_therapy
gptkb:CAR_T-cell_therapy |
| gptkbp:development |
from hematopoietic stem cells
|
| gptkbp:displacement |
effector T cells
naive T cells central memory T cells effector memory T cells |
| gptkbp:function |
adaptive immunity
|
| https://www.w3.org/2000/01/rdf-schema#label |
T cells
|
| gptkbp:influence |
immune response
|
| gptkbp:initiated_by |
antigen presentation
cytokines superantigens |
| gptkbp:interacts_with |
B cells
|
| gptkbp:involved_in |
allergic reactions
autoimmune diseases viral infections cancer immunotherapy |
| gptkbp:is_affected_by |
gptkb:HIV
immunosuppressive drugs |
| gptkbp:is_involved_in |
pathogen clearance
neuroinflammation tumor microenvironment inflammatory responses chronic inflammation tissue repair graft rejection transplantation immunology environmental exposures chronic infections host defense metabolic regulation microbiome interactions immune checkpoint inhibition vaccine responses immune surveillance T cell exhaustion aging-related immune decline chronic disease progression immune system homeostasis |
| gptkbp:is_studied_in |
cell culture
flow cytometry immunohistochemistry |
| gptkbp:memory_function |
long-term immunity
|
| gptkbp:occurs_in |
apoptosis
clonal expansion |
| gptkbp:origin |
thymus
|
| gptkbp:produces |
cytokines
|
| gptkbp:replaces |
bone marrow
lymph nodes peripheral blood |
| gptkbp:requires |
MHC molecules for recognition
co-stimulation for activation |
| gptkbp:role |
helping other immune cells
killing infected cells |
| gptkbp:surface_markers |
CD4
CD8 |
| gptkbp:type_of |
cytotoxic T cells
helper T cells regulatory T cells memory T cells |
| gptkbp:bfsParent |
gptkb:Stelara
gptkb:HOT3 gptkb:interferon-gamma gptkb:White_Blood_Cells gptkb:Science_Immunology gptkb:IL-2_M gptkb:IL-2_M3 |
| gptkbp:bfsLayer |
5
|