|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:E2A
gptkb:Immunoglobulin_enhancer-binding_factor_E12/E47
|
|
gptkbp:alternativeSplicing
|
gptkb:E12
gptkb:E47
|
|
gptkbp:associatedWith
|
gptkb:pre-B-cell_acute_lymphoblastic_leukemia
|
|
gptkbp:encodes
|
gptkb:Transcription_factor_E2-alpha
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000118351
6929
|
|
gptkbp:expressedIn
|
gptkb:B_cells
gptkb:T_cells
muscle cells
|
|
gptkbp:formsFusionGeneWith
|
gptkb:TCF3
gptkb:EP300
gptkb:PBX1
gptkb:TCF4
gptkb:HLF
gptkb:TCF12
gptkb:SPI1
gptkb:HNRNPH1
gptkb:NCOA1
gptkb:KMT2A
gptkb:ZNF384
gptkb:FLI1
BCL9
|
|
gptkbp:formsHeterodimerWith
|
gptkb:TCF4
gptkb:MYOD1
gptkb:TCF12
gptkb:MYF5
gptkb:MYOG
MYF6
|
|
gptkbp:function
|
transcription factor
regulation of gene expression
|
|
gptkbp:HGNC_ID
|
HGNC:11633
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TCF3 (E2A)
|
|
gptkbp:interactsWith
|
gptkb:GATA1
gptkb:GATA2
gptkb:LMO2
gptkb:GATA3
gptkb:CBP
gptkb:TCF4
gptkb:RUNX1
gptkb:PAX5
gptkb:ID2
gptkb:ID3
gptkb:ID4
gptkb:MYOD1
gptkb:TCF12
gptkb:p300
gptkb:MYF5
gptkb:MYOG
gptkb:LMO1
gptkb:LMO3
gptkb:LMO4
ID1
EBF1
MYF6
|
|
gptkbp:locatedOnChromosome
|
gptkb:19p13.3
|
|
gptkbp:memberOf
|
gptkb:basic_helix-loop-helix_(bHLH)_family
|
|
gptkbp:mutationAssociatedWith
|
leukemia
immunodeficiency
|
|
gptkbp:OMIM
|
147141
|
|
gptkbp:orthologInMouse
|
gptkb:Tcf3
|
|
gptkbp:orthologInZebrafish
|
tcf3a
tcf3b
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
cell proliferation
immunoglobulin gene expression
|
|
gptkbp:UniProtID
|
P15923
|
|
gptkbp:bfsParent
|
gptkb:t(1;19)_translocation
|
|
gptkbp:bfsLayer
|
7
|