pre-B-cell acute lymphoblastic leukemia

URI: https://gptkb.org/entity/pre-B-cell_acute_lymphoblastic_leukemia
GPTKB entity
Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:disease
leukemia
acute lymphoblastic leukemia subtype
gptkbp:affects hematopoietic system
gptkbp:commonIn children
gptkbp:diagnosedBy bone marrow biopsy
cytogenetic analysis
immunophenotyping
flow cytometry
gptkbp:hasGeneticAlteration gptkb:t(12;21)_ETV6-RUNX1
gptkb:t(9;22)_BCR-ABL
hyperdiploidy
hypodiploidy
https://www.w3.org/2000/01/rdf-schema#label pre-B-cell acute lymphoblastic leukemia
gptkbp:ICD-10_code gptkb:C91.0
gptkbp:marking gptkb:CD22
gptkb:CD34
gptkb:CD10
gptkb:TdT
gptkb:CD19
gptkbp:occurredIn adults
gptkbp:originatedIn pre-B lymphoblast
gptkbp:prognosis age
white blood cell count
cytogenetic abnormalities
response to therapy
gptkbp:riskFactor gptkb:Down_syndrome
radiation exposure
genetic predisposition
gptkbp:signature gptkb:anemia
hepatosplenomegaly
lymphadenopathy
thrombocytopenia
leukocytosis
gptkbp:symptom fever
bleeding
fatigue
recurrent infections
bone pain
easy bruising
gptkbp:synonym gptkb:B-precursor_acute_lymphoblastic_leukemia
gptkb:pre-B_ALL
gptkb:precursor_B-cell_acute_lymphoblastic_leukemia
gptkbp:treatment chemotherapy
immunotherapy
stem cell transplantation
corticosteroids
tyrosine kinase inhibitors
gptkbp:bfsParent gptkb:PBX1
gptkb:Pre-B-cell_leukemia_homeobox_protein
gptkbp:bfsLayer 6