|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:RBTN2
gptkb:Rhombotin-2
gptkb:T-cell_translocation_gene_2
gptkb:TTG2
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:T-cell_acute_lymphoblastic_leukemia
angiogenesis
|
|
gptkbp:discoveredBy
|
gptkb:T._Rabbitts
|
|
gptkbp:domain
|
gptkb:LIM_domain
|
|
gptkbp:encodes
|
gptkb:LIM_domain_only_protein_2
|
|
gptkbp:Entrez_Gene_ID
|
4005
ENSG00000142794
|
|
gptkbp:expressedIn
|
endothelial cells
hematopoietic stem cells
|
|
gptkbp:firstDescribed
|
1992
|
|
gptkbp:fullName
|
gptkb:LIM_domain_only_2
|
|
gptkbp:function
|
transcriptional regulator
|
|
gptkbp:geneLocationEnd
|
33826413
|
|
gptkbp:geneLocationStart
|
33815541
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:6637
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
LMO2
|
|
gptkbp:interactsWith
|
gptkb:GATA1
gptkb:TAL1
gptkb:E47
gptkb:LDB1
|
|
gptkbp:involvedIn
|
hematopoiesis
|
|
gptkbp:length
|
158 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p13
|
|
gptkbp:molecularWeight
|
17 kDa
|
|
gptkbp:mutationAssociatedWith
|
leukemia
|
|
gptkbp:OMIM
|
180385
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Lmo2
|
|
gptkbp:orthologInZebrafish
|
lmo2
|
|
gptkbp:pathway
|
gptkb:hematopoietic_cell_lineage
angiogenesis
|
|
gptkbp:proteinFamily
|
gptkb:LIM-only_proteins
|
|
gptkbp:referenceGenome
|
gptkb:GRCh38
|
|
gptkbp:regulates
|
gene expression
|
|
gptkbp:significance
|
biomarker for leukemia
target for gene therapy
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
P25791
|
|
gptkbp:bfsParent
|
gptkb:HBB
gptkb:LMO
|
|
gptkbp:bfsLayer
|
6
|