|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:E12
gptkb:E2A
gptkb:E47
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
leukemia
|
|
gptkbp:encodes
|
gptkb:Transcription_factor_E2-alpha
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000071564
6929
|
|
gptkbp:expressedIn
|
lymphoid tissues
|
|
gptkbp:formsFusionGeneWith
|
gptkb:PBX1
gptkb:HLF
|
|
gptkbp:fullName
|
gptkb:Transcription_factor_3
|
|
gptkbp:function
|
regulation of gene expression
DNA binding
transcription factor activity
B-cell development
lymphocyte differentiation
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GOProcess
|
B cell differentiation
regulation of transcription, DNA-templated
|
|
gptkbp:HGNC_ID
|
11633
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TCF3
|
|
gptkbp:interactsWith
|
gptkb:E2-2
gptkb:HEB
gptkb:ID_proteins
|
|
gptkbp:length
|
654 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:19p13.3
|
|
gptkbp:memberOf
|
basic helix-loop-helix (bHLH) transcription factors
|
|
gptkbp:molecularWeight
|
68 kDa
|
|
gptkbp:mutationAssociatedWith
|
leukemia
immunodeficiency
|
|
gptkbp:OMIM
|
147141
|
|
gptkbp:orthologInMouse
|
gptkb:Tcf3
|
|
gptkbp:regulates
|
apoptosis
cell cycle
immunoglobulin gene rearrangement
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
P15923
|
|
gptkbp:bfsParent
|
gptkb:ITF1
|
|
gptkbp:bfsLayer
|
5
|