|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:BSAP
B-cell specific activator protein
|
|
gptkbp:associatedWith
|
leukemia
|
|
gptkbp:discoveredBy
|
Stephan Busslinger
|
|
gptkbp:domain
|
homeodomain-like
paired box domain
|
|
gptkbp:encodes
|
Paired box protein Pax-5
|
|
gptkbp:Entrez_Gene_ID
|
5079
ENSG00000196092
|
|
gptkbp:expressedIn
|
gptkb:B_lymphocytes
|
|
gptkbp:firstDescribed
|
1992
|
|
gptkbp:fullName
|
Paired box protein Pax-5
|
|
gptkbp:function
|
transcription factor
B-cell development
|
|
gptkbp:HGNC_ID
|
HGNC:8617
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PAX5
|
|
gptkbp:length
|
391 amino acids
|
|
gptkbp:locatedOnChromosome
|
9
9p13.2
|
|
gptkbp:molecularWeight
|
42 kDa
|
|
gptkbp:mutationAssociatedWith
|
impaired B-cell development
|
|
gptkbp:OMIM
|
167414
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Pax5
|
|
gptkbp:proteinFamily
|
PAX family
|
|
gptkbp:regulates
|
gptkb:CD19
B-cell lineage commitment
|
|
gptkbp:splicing_variants
|
multiple
|
|
gptkbp:targetGene
|
gptkb:Pik3cd
gptkb:Syk
gptkb:IGHM
gptkb:BLNK
gptkb:MB-1
gptkb:CD19
gptkb:Foxo1
gptkb:LEF1
gptkb:Pik3r1
gptkb:CD79A
gptkb:RAG1
gptkb:RAG2
gptkb:Ptpn6
gptkb:CD79B
Cd19
Ptpn22
Ighm
Blnk
Cd79a
Cd79b
EBF1
Ebf1
Flt3
IL7R
Lef1
Mb-1
VpreB1
VpreB2
Vpreb1
Vpreb2
|
|
gptkbp:transcription_regulation
|
activator
repressor
|
|
gptkbp:UniProtID
|
Q02548
|
|
gptkbp:bfsParent
|
gptkb:B-cell_ALL
gptkb:Reed-Sternberg_cell
|
|
gptkbp:bfsLayer
|
6
|