Transcription factor E2-alpha
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
produces E12 and E47 isoforms
|
| gptkbp:associatedWith |
gptkb:t(1;19)_translocation
leukemia |
| gptkbp:domain |
basic helix-loop-helix (bHLH) domain
|
| gptkbp:encodedBy |
gptkb:TCF3_gene
|
| gptkbp:expressedIn |
hematopoietic cells
|
| gptkbp:function |
transcription factor
regulation of gene expression |
| gptkbp:gene |
gptkb:TCF3
|
| gptkbp:HGNC_ID |
11633
|
| https://www.w3.org/2000/01/rdf-schema#label |
Transcription factor E2-alpha
|
| gptkbp:interactsWith |
gptkb:E2-2
gptkb:HEB gptkb:ID_proteins |
| gptkbp:involves |
B-cell development
lymphocyte differentiation |
| gptkbp:locatedOnChromosome |
gptkb:19p13.3
|
| gptkbp:location |
gptkb:nucleus
|
| gptkbp:member |
gptkb:E-protein_family
|
| gptkbp:molecularWeight |
~70 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Tcf3
|
| gptkbp:regulates |
apoptosis
cell cycle immunoglobulin gene rearrangement |
| gptkbp:UniProtID |
P15923
|
| gptkbp:bfsParent |
gptkb:ITF1
|
| gptkbp:bfsLayer |
5
|