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gptkbp:instanceOf
|
biological pathway
|
|
gptkbp:activatedBy
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gptkb:MAPK_pathway
gptkb:Ral-GDS_pathway
gptkb:PI3K-Akt_pathway
|
|
gptkbp:component
|
signal transduction
|
|
gptkbp:foundIn
|
eukaryotic cells
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Ras signaling pathway
|
|
gptkbp:involves
|
gptkb:14-3-3_proteins
gptkb:Akt
gptkb:Tiam1
gptkb:HRAS
gptkb:KRAS
gptkb:NRAS
gptkb:PI3K
gptkb:RAF_kinase
gptkb:CDC42
gptkb:GRB2_protein
gptkb:NF1_protein
gptkb:PLCĪµ
gptkb:RASSF_proteins
gptkb:Rac1
gptkb:Raf/MEK/ERK_cascade
gptkb:SOS_protein
gptkb:ERK
gptkb:MEK
gptkb:RalA
gptkb:RalB
gptkb:Ras_protein
gptkb:Sprouty_proteins
gptkb:mTOR
farnesylation
guanine nucleotide exchange factor
palmitoylation
phosphorylation
histone modification
ubiquitination
GAP proteins
GDP-GTP exchange
GEF proteins
membrane localization
|
|
gptkbp:launched
|
gptkb:receptor_tyrosine_kinases
growth factor receptors
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:Cardiofaciocutaneous_syndrome
gptkb:Costello_syndrome
gptkb:Noonan_syndrome
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
cell proliferation
cell survival
gene expression
|
|
gptkbp:bfsParent
|
gptkb:RalGDS
gptkb:RalGEF_pathway
|
|
gptkbp:bfsLayer
|
5
|