Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:MEK1
gptkb:MEK2 |
| gptkbp:alternativeName |
gptkb:MAPK1
gptkb:MAPK3 gptkb:p42_MAPK gptkb:p44_MAPK |
| gptkbp:discoveredIn |
1991
|
| gptkbp:encodedBy |
gptkb:MAPK1_gene
gptkb:MAPK3_gene |
| gptkbp:family |
gptkb:MAP_kinase_family
|
| gptkbp:fullName |
gptkb:Extracellular_signal-regulated_kinase
|
| gptkbp:function |
signal transduction
regulation of cell division regulation of differentiation regulation of proliferation |
| https://www.w3.org/2000/01/rdf-schema#label |
ERK
|
| gptkbp:inhibitedBy |
gptkb:PD98059
gptkb:U0126 |
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:pathway |
gptkb:Ras-Raf-MEK-ERK_pathway
|
| gptkbp:phosphorylates |
transcription factors
cytoskeletal proteins other kinases |
| gptkbp:regulates |
gene expression
|
| gptkbp:relatedTo |
gptkb:cancer
apoptosis cellular response to growth factors |
| gptkbp:species |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:bfsParent |
gptkb:MAPK/ERK_pathway
|
| gptkbp:bfsLayer |
5
|