|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:glioblastoma
colorectal cancer
melanoma
schizophrenia
neurodevelopmental disorders
mental retardation
|
|
gptkbp:biologicalProcess
|
GTPase activity
|
|
gptkbp:encodedBy
|
gptkb:RAC1_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000136238
5879
|
|
gptkbp:family
|
gptkb:Rho_family
|
|
gptkbp:fullName
|
gptkb:Ras-related_C3_botulinum_toxin_substrate_1
|
|
gptkbp:function
|
cell proliferation
cell cycle progression
cell migration
cell adhesion
regulation of actin cytoskeleton
|
|
gptkbp:HGNC_ID
|
9801
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Rac1
|
|
gptkbp:interactsWith
|
gptkb:PAK1
gptkb:Tiam1
gptkb:WAVE_complex
gptkb:GIT1
gptkb:DOCK180
gptkb:ELMO1
gptkb:IQGAP1
gptkb:NADPH_oxidase
|
|
gptkbp:length
|
192 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:7p22
|
|
gptkbp:location
|
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:molecularWeight
|
21 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Caenorhabditis_elegans
gptkb:Drosophila_melanogaster
|
|
gptkbp:PDB
|
gptkb:1MH1
gptkb:2W2T
|
|
gptkbp:postTranslationalModification
|
prenylation
phosphorylation
sumoylation
ubiquitination
|
|
gptkbp:regulates
|
activated by GEFs
inactivated by GAPs
regulated by GDIs
|
|
gptkbp:structure
|
gptkb:GTP-binding_domain
|
|
gptkbp:subfamily
|
gptkb:Rac_subfamily
|
|
gptkbp:UniProtID
|
gptkb:P63000
|
|
gptkbp:bfsParent
|
gptkb:Rho_family
gptkb:Ras_signaling_pathway
|
|
gptkbp:bfsLayer
|
6
|