NF1 protein

URI: https://gptkb.org/entity/NF1_protein

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alsoKnownAs	gptkb:neurofibromin
gptkbp:chromosomalLocationOfGene	gptkb:17q11.2
gptkbp:discoveredIn	1990
gptkbp:domain	gptkb:GRD_(GAP-related_domain) gptkb:PH-like_domain gptkb:Sec14-like_domain
gptkbp:encodedBy	gptkb:NF1_gene
gptkbp:function	gptkb:GTPase-activating_protein tumor suppressor
https://www.w3.org/2000/01/rdf-schema#label	NF1 protein
gptkbp:interactsWith	gptkb:Ras_proteins gptkb:SPRED1 microtubules
gptkbp:locale	gptkb:nucleus gptkb:cytoplasm
gptkbp:molecularWeight	~320 kDa
gptkbp:mutationAssociatedWith	gptkb:neurofibromatosis_type_1
gptkbp:orthologInDrosophila	gptkb:dNf1_protein
gptkbp:orthologInMouse	gptkb:Nf1_protein
gptkbp:regulates	gptkb:Ras_signaling_pathway
gptkbp:bfsParent	gptkb:Ras_signaling_pathway
gptkbp:bfsLayer	6