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gptkbp:instanceOf
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gptkb:protein
|
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gptkbp:alternativeName
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gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog
gptkb:Transforming_protein_p21
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gptkbp:associatedWith
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gptkb:cancer
gptkb:Costello_syndrome
colorectal cancer
bladder cancer
gastric cancer
|
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gptkbp:enzymeClassification
|
gptkb:EC_3.6.5.2
|
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gptkbp:family
|
gptkb:Ras_family
|
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gptkbp:function
|
signal transduction
GTPase activity
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gptkbp:gene
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gptkb:HRAS
|
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gptkbp:GO_term
|
GTP binding
regulation of cell proliferation
MAPK cascade
plasma membrane localization
protein signal transduction
small GTPase mediated signal transduction
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https://www.w3.org/2000/01/rdf-schema#label
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RASH HUMAN
|
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gptkbp:interactsWith
|
gptkb:MAPK1
gptkb:MAPK3
gptkb:NF1
gptkb:PLCE1
gptkb:RAP1A
gptkb:RASA1
gptkb:RIN1
gptkb:ARAF
gptkb:BRAF
gptkb:GRB2
gptkb:PIK3CA
gptkb:RAF1
gptkb:RALGDS
gptkb:SOS1
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|
gptkbp:length
|
189 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p15.5
|
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gptkbp:location
|
gptkb:cell_membrane
gptkb:cytoplasm
|
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gptkbp:molecularWeight
|
21 kDa
|
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gptkbp:mutationAssociatedWith
|
gptkb:G12V
gptkb:G13D
gptkb:Q61L
A59T
Q61R
T58I
|
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gptkbp:organism
|
gptkb:Homo_sapiens
|
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gptkbp:PDB
|
gptkb:5P21
1AA9
4Q21
|
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gptkbp:postTranslationalModification
|
farnesylation
palmitoylation
phosphorylation
|
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gptkbp:UniProtID
|
gptkb:P01112
|
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gptkbp:bfsParent
|
gptkb:UniProt:P01112
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gptkbp:bfsLayer
|
5
|