|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog
gptkb:Transforming_protein_p21
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Bladder_cancer
gptkb:Costello_syndrome
gptkb:Gastric_cancer
Leukemia
|
|
gptkbp:discoveredBy
|
1982
|
|
gptkbp:EC_number
|
3.6.5.2
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSP00000256078
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:family
|
gptkb:Ras_family
|
|
gptkbp:function
|
gptkb:Signal_transduction
GTPase activity
|
|
gptkbp:gene
|
gptkb:HRAS
|
|
gptkbp:GO_term
|
GTP binding
plasma membrane localization
protein signal transduction
|
|
gptkbp:hasIsoform
|
P01112-1
|
|
gptkbp:HGNC_ID
|
5173
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P01112
|
|
gptkbp:InterPro
|
gptkb:IPR001806
|
|
gptkbp:KEGGID
|
gptkb:hsa:3265
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p15.5
|
|
gptkbp:molecularWeight
|
21 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:G12V
gptkb:G13D
gptkb:Q61L
|
|
gptkbp:OMIM
|
190020
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Danio_rerio_hras
gptkb:Mus_musculus_Hras
gptkb:Rattus_norvegicus_Hras
|
|
gptkbp:PDB
|
gptkb:5P21
1AA9
|
|
gptkbp:postTranslationalModification
|
Farnesylation
Palmitoylation
|
|
gptkbp:protein_name
|
gptkb:GTPase_HRas
|
|
gptkbp:proteinFamily
|
gptkb:PF00071
|
|
gptkbp:Reactome
|
gptkb:R-HSA-5673001
|
|
gptkbp:RefSeq
|
gptkb:NP_005334.1
|
|
gptkbp:reviewedBy
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:sequence
|
189
|
|
gptkbp:sequenceStatus
|
complete
|
|
gptkbp:subcellularLocation
|
gptkb:Cell_membrane
gptkb:Cytoplasm
|
|
gptkbp:superfamily
|
Small GTPase superfamily
|
|
gptkbp:UniProtID
|
gptkb:P01112
|
|
gptkbp:bfsParent
|
gptkb:HRAS
gptkb:UniProt:P01112
|
|
gptkbp:bfsLayer
|
5
|