|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog
gptkb:Transforming_protein_p21
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Bladder_cancer
gptkb:Costello_syndrome
gptkb:Gastric_cancer
gptkb:Head_and_neck_squamous_cell_carcinoma
|
|
gptkbp:biologicalProcess
|
cell proliferation
signal transduction
GTP binding
GTPase activity
|
|
gptkbp:disulfideBond
|
Cys181-Cys184
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSP00000256078
3265
GC11P005334
|
|
gptkbp:enzymeCommissionNumber
|
gptkb:EC_3.6.5.2
|
|
gptkbp:family
|
gptkb:small_GTPase_superfamily
|
|
gptkbp:function
|
Molecular switch in signal transduction
|
|
gptkbp:gene
|
gptkb:HRAS
|
|
gptkbp:hasIsoform
|
1
|
|
gptkbp:HGNC_ID
|
5173
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
UniProt:P01112
|
|
gptkbp:is_reviewed
|
true
|
|
gptkbp:KEGGID
|
gptkb:hsa:3265
|
|
gptkbp:locatedOnChromosome
|
11
|
|
gptkbp:location
|
gptkb:11p15.5
|
|
gptkbp:mass
|
21 kDa
|
|
gptkbp:OMIM
|
190020
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
|
|
gptkbp:PDB
|
gptkb:5P21
1AA9
3K8Y
|
|
gptkbp:postTranslationalModification
|
Farnesylation
Methylation
Palmitoylation
|
|
gptkbp:protein_name
|
gptkb:GTPase_HRas
|
|
gptkbp:Reactome
|
gptkb:R-HSA-5673001
|
|
gptkbp:RefSeq
|
gptkb:NP_005334.1
|
|
gptkbp:sequence
|
189
|
|
gptkbp:sequenceStatus
|
complete
|
|
gptkbp:subcellularLocation
|
gptkb:Cell_membrane
gptkb:Cytoplasm
gptkb:Golgi_apparatus
|
|
gptkbp:subfamily
|
gptkb:Ras_family
|
|
gptkbp:UniProt_entry_name
|
gptkb:RASH_HUMAN
|
|
gptkbp:UniProtID
|
gptkb:P01112
|
|
gptkbp:bfsParent
|
gptkb:RAS
|
|
gptkbp:bfsLayer
|
4
|