gptkbp:instanceOf
|
gptkb:gene
|
gptkbp:alternativeName
|
gptkb:Krev-1
gptkb:Ras-related_protein_Rap-1A
|
gptkbp:associatedWith
|
gptkb:Kabuki_syndrome
|
gptkbp:discoveredBy
|
gptkb:Kitayama_et_al.
|
gptkbp:discoveredIn
|
1989
|
gptkbp:encodes
|
gptkb:Ras-related_protein_Rap-1A
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000116473
5906
|
gptkbp:expressedIn
|
various tissues
|
gptkbp:function
|
signal transduction
GTPase activity
|
gptkbp:geneType
|
protein-coding
|
gptkbp:GO_term
|
GO:0005525
GO:0007165
GO:0007264
|
gptkbp:hasParalog
|
gptkb:RAP1B
|
gptkbp:HGNC_ID
|
9862
|
https://www.w3.org/2000/01/rdf-schema#label
|
RAP1A
|
gptkbp:interactsWith
|
gptkb:RAPGEF1
gptkb:RAPGEF2
gptkb:RAPGEF3
gptkb:RAPGEF4
gptkb:RAPGEF5
gptkb:RAPGEF6
gptkb:EPAC1
gptkb:EPAC2
gptkb:RAP1GAP2
gptkb:RASA3
gptkb:RAP1GAP
|
gptkbp:length
|
184 amino acids
|
gptkbp:locatedOnChromosome
|
chromosome 1
|
gptkbp:memberOf
|
gptkb:Ras_family
|
gptkbp:molecularWeight
|
20.7 kDa
|
gptkbp:OMIM
|
179530
|
gptkbp:orthologInMouse
|
gptkb:Rap1a
|
gptkbp:PDB
|
gptkb:1C1Y
gptkb:1GUA
1Q21
|
gptkbp:postTranslationalModification
|
farnesylation
phosphorylation
|
gptkbp:regulates
|
cell proliferation
cell adhesion
cell junction formation
integrin-mediated signaling
|
gptkbp:species
|
gptkb:Homo_sapiens
|
gptkbp:subcellularLocation
|
gptkb:cytoplasm
gptkb:plasma_membrane
endosomes
|
gptkbp:UniProtID
|
gptkb:P62834
|
gptkbp:bfsParent
|
gptkb:Ras_gene_family
|
gptkbp:bfsLayer
|
5
|