|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:GEF
gptkb:Son_of_sevenless_1
|
|
gptkbp:associatedWith
|
gptkb:hereditary_gingival_fibromatosis
gptkb:Noonan_syndrome
|
|
gptkbp:biologicalProcess
|
signal transduction
MAPK cascade
Ras guanyl-nucleotide exchange factor activity
|
|
gptkbp:cellularComponent
|
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:Entrez_Gene_ID
|
6654
ENSG00000115904
|
|
gptkbp:fullName
|
gptkb:Son_of_sevenless_homolog_1
|
|
gptkbp:function
|
guanine nucleotide exchange factor
activates RAS proteins
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
11187
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SOS1
|
|
gptkbp:interactsWith
|
gptkb:EGFR
gptkb:RAS_proteins
gptkb:GRB2
|
|
gptkbp:length
|
1333
|
|
gptkbp:locatedOnChromosome
|
2
2p22-p16
|
|
gptkbp:mutationAssociatedWith
|
developmental disorders
|
|
gptkbp:OMIM
|
182530
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Drosophila_sevenless_gene
|
|
gptkbp:product
|
gptkb:SOS1_protein
|
|
gptkbp:RefSeq
|
NM_005633
|
|
gptkbp:UniProtID
|
Q07889
|
|
gptkbp:bfsParent
|
gptkb:HRAS
|
|
gptkbp:bfsLayer
|
5
|