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gptkbp:instanceOf
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gptkb:protein
|
|
gptkbp:alternativeName
|
PKC-alpha
PRKCA_HUMAN
Protein kinase C, alpha type
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gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:cancer
gptkb:cardiovascular_disease
|
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gptkbp:biologicalProcess
|
angiogenesis
ATP binding
MAPK cascade
protein kinase activity
cellular response to tumor necrosis factor
positive regulation of cell migration
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|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
gptkb:plasma_membrane
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gptkbp:Entrez_Gene_ID
|
5578
ENSG00000154229
|
|
gptkbp:enzymeClassification
|
EC 2.7.11.13
|
|
gptkbp:fullName
|
gptkb:Protein_kinase_C_alpha_type
|
|
gptkbp:function
|
cell differentiation
signal transduction
regulation of apoptosis
regulation of cell proliferation
serine/threonine-protein kinase activity
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gptkbp:gene
|
gptkb:PRKCA
|
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gptkbp:HGNC_ID
|
HGNC:9393
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PRKCA
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gptkbp:interactsWith
|
gptkb:AKT1
gptkb:EGFR
gptkb:MAPK1
gptkb:SRC
gptkb:VIM
gptkb:GRB2
gptkb:RAF1
gptkb:BCL2
gptkb:TP53
gptkb:GAPDH
|
|
gptkbp:locatedOnChromosome
|
17
|
|
gptkbp:location
|
17q24.2
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Prkca
rat Prkca
zebrafish prkca
|
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gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:Wnt_signaling_pathway
gptkb:Calcium_signaling_pathway
|
|
gptkbp:UniProtID
|
P17252
|
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gptkbp:bfsParent
|
gptkb:PKC
|
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gptkbp:bfsLayer
|
6
|