|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alias
|
gptkb:GAPD
gptkb:OK/SW-cl.12
gptkb:G3PD
|
|
gptkbp:alternativeTo
|
involved in apoptosis
involved in DNA repair
involved in membrane fusion
involved in transcription regulation
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:Parkinson's_disease
gptkb:cancer
|
|
gptkbp:biologicalProcess
|
oxidoreductase activity
glycolytic process
|
|
gptkbp:cofactor
|
NAD+
|
|
gptkbp:discoveredBy
|
gptkb:Gustav_Embden
|
|
gptkbp:EC_number
|
1.2.1.12
|
|
gptkbp:Ensembl_(human)
|
gptkb:ENSG00000111640
|
|
gptkbp:expressedIn
|
all tissues
|
|
gptkbp:fullName
|
gptkb:glyceraldehyde-3-phosphate_dehydrogenase
|
|
gptkbp:function
|
catalyzes the sixth step of glycolysis
|
|
gptkbp:gene
|
gptkb:GAPDH
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GAPDH
|
|
gptkbp:inhibitedBy
|
iodoacetate
hydroxylamine
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_12p13.31
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
36 kDa
|
|
gptkbp:organism
|
gptkb:Mus_musculus
gptkb:Saccharomyces_cerevisiae
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
present in all domains of life
|
|
gptkbp:pathway
|
glycolysis
gluconeogenesis
|
|
gptkbp:PDB
|
1U8F
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
S-nitrosylation
|
|
gptkbp:product
|
gptkb:H+
gptkb:NADH
1,3-bisphosphoglycerate
|
|
gptkbp:quaternary_structure
|
homotetramer
|
|
gptkbp:RefSeq_(human)
|
gptkb:NM_002046
|
|
gptkbp:substrate
|
glyceraldehyde-3-phosphate
|
|
gptkbp:UniProtID
|
P04406
|
|
gptkbp:usedFor
|
housekeeping gene
loading control in Western blot
|
|
gptkbp:bfsParent
|
gptkb:P49327
gptkb:glyceraldehyde-3-phosphate_dehydrogenase
gptkb:PRKCA
gptkb:P04424
|
|
gptkbp:bfsLayer
|
7
|