|
gptkbp:instanceOf
|
gptkb:protein
gptkb:enzyme
|
|
gptkbp:activatedBy
|
calcium
phospholipids
diacylglycerol
|
|
gptkbp:alias
|
gptkb:AAG6
gptkb:MGC129900
gptkb:PKCA
gptkb:PRKACA
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:cancer
gptkb:cardiovascular_disease
|
|
gptkbp:EC_number
|
2.7.11.13
|
|
gptkbp:encodedBy
|
gptkb:PRKCA_gene
|
|
gptkbp:fullName
|
gptkb:Protein_kinase_C_alpha_type
|
|
gptkbp:function
|
signal transduction
regulation of apoptosis
regulation of cell proliferation
serine/threonine-protein kinase activity
regulation of gene expression
|
|
gptkbp:gene
|
gptkb:PRKCA
|
|
gptkbp:GO_term
|
gptkb:GO:0004697
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PKCα
|
|
gptkbp:inhibitedBy
|
gptkb:chelerythrine
gptkb:staurosporine
|
|
gptkbp:locatedOnChromosome
|
gptkb:17q24
|
|
gptkbp:location
|
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:memberOf
|
gptkb:protein_kinase_C_family
|
|
gptkbp:molecularWeight
|
80 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:phospholipase_D_signaling_pathway
calcium signaling pathway
|
|
gptkbp:PDB
|
gptkb:4RA4
3IW4
|
|
gptkbp:phosphorylates
|
gptkb:GAP-43
gptkb:MARCKS
gptkb:myristoylated_alanine-rich_C-kinase_substrate
|
|
gptkbp:UniProtID
|
P17252
|
|
gptkbp:bfsParent
|
gptkb:mTORC2
|
|
gptkbp:bfsLayer
|
6
|