Protein kinase C alpha type

URI: https://gptkb.org/entity/Protein_kinase_C_alpha_type
GPTKB entity
Statements (53)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy phospholipids
calcium ions
diacylglycerol
gptkbp:alternativeName gptkb:PRKCA
PKC-alpha
gptkbp:associatedWith gptkb:Alzheimer's_disease
gptkb:cancer
gptkb:cardiovascular_disease
gptkbp:biologicalProcess ATP binding
protein kinase activity
protein binding
gptkbp:cellularComponent gptkb:nucleus
gptkb:cytoplasm
gptkb:plasma_membrane
gptkbp:encodedBy gptkb:PRKCA_gene
gptkbp:enzymeCommissionNumber 2.7.11.13
gptkbp:foundIn gptkb:cancer
gptkb:skeletal_muscle
gptkb:kidney
gptkb:testis
brain
heart
liver
spleen
pancreas
gptkbp:function serine/threonine-protein kinase activity
https://www.w3.org/2000/01/rdf-schema#label Protein kinase C alpha type
gptkbp:involvedIn apoptosis
cell differentiation
cell proliferation
signal transduction
gptkbp:length 672 amino acids
gptkbp:locatedOnChromosome 17q24-q25
gptkbp:mass 77 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologIn gptkb:Mus_musculus
gptkb:Rattus_norvegicus
gptkbp:phosphorylates GAP-43 protein
MARCKS protein
gptkbp:postTranslationalModification phosphorylation
ubiquitination
gptkbp:regulates gene expression
cell migration
cell cycle
cell adhesion
gptkbp:structure contains C1 and C2 domains
gptkbp:UniProtID P17252
gptkbp:bfsParent gptkb:PKCĪ±
gptkb:P17252_(PKC_alpha)
gptkb:PKC_alpha
gptkb:PRKCA
gptkbp:bfsLayer 7