|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:abbreviation
|
gptkb:Protein_kinase_C
|
|
gptkbp:activatedBy
|
phorbol esters
calcium ions
diacylglycerol
|
|
gptkbp:category
|
gptkb:enzyme
signal transduction protein
|
|
gptkbp:discoveredBy
|
gptkb:Yasutomi_Nishizuka
|
|
gptkbp:discoveredIn
|
1977
|
|
gptkbp:EC_number
|
2.7.11.13
|
|
gptkbp:family
|
serine/threonine kinases
|
|
gptkbp:function
|
phosphorylation of serine and threonine residues
|
|
gptkbp:hasIsoform
|
gptkb:PKC_alpha
gptkb:PKC_beta
gptkb:PKC_delta
gptkb:PKC_epsilon
gptkb:PKC_eta
gptkb:PKC_gamma
gptkb:PKC_iota
gptkb:PKC_theta
gptkb:PKC_zeta
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PKC
|
|
gptkbp:inhibitedBy
|
gptkb:Gö_6983
gptkb:bisindolylmaleimide
gptkb:chelerythrine
gptkb:staurosporine
|
|
gptkbp:involvedIn
|
apoptosis
cell proliferation
differentiation
signal transduction
gene expression regulation
|
|
gptkbp:locale
|
gptkb:nucleus
gptkb:Golgi_apparatus
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:proteinFamily
|
gptkb:PRKCA
gptkb:PRKCB
gptkb:PRKCD
gptkb:PRKCE
gptkb:PRKCG
gptkb:PRKCH
gptkb:PRKCI
gptkb:PRKCQ
gptkb:PRKCZ
|
|
gptkbp:relatedTo
|
gptkb:cancer
gptkb:cardiovascular_disease
gptkb:diabetes
neurodegenerative disease
|
|
gptkbp:UniProtID
|
gptkb:P05129_(PKC_gamma)
gptkb:P05771_(PKC_beta)
gptkb:P17252_(PKC_alpha)
gptkb:Q02154_(PKC_eta)
gptkb:Q02156_(PKC_epsilon)
Q04759 (PKC theta)
Q05513 (PKC zeta)
Q05655 (PKC delta)
Q13423 (PKC iota)
|
|
gptkbp:bfsParent
|
gptkb:Аэропорт_Елизово
|
|
gptkbp:bfsLayer
|
5
|