|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:acute_myeloid_leukemia
melanoma
|
|
gptkbp:discoveredIn
|
1983
|
|
gptkbp:encodedBy
|
gptkb:NRAS_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000213281
4893
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
gptkb:neuroblastoma_RAS_viral_oncogene_homolog
|
|
gptkbp:function
|
guanine nucleotide exchange factor
signal transduction
|
|
gptkbp:gene
|
gptkb:NRAS
|
|
gptkbp:HGNC_ID
|
7989
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NRas
|
|
gptkbp:interactsWith
|
gptkb:GAPs
gptkb:GEFs
gptkb:PI3K
gptkb:GRB2
gptkb:RAF1
gptkb:SOS1
|
|
gptkbp:locatedIn
|
gptkb:human_chromosome_1
|
|
gptkbp:memberOf
|
gptkb:RAS_family
|
|
gptkbp:mutationAssociatedWith
|
oncogenic
codon 12
codon 13
codon 61
|
|
gptkbp:OMIM
|
164790
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
|
|
gptkbp:postTranslationalModification
|
farnesylation
palmitoylation
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
cell proliferation
|
|
gptkbp:relatedTo
|
gptkb:HRas
gptkb:KRas
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:subcellularLocation
|
gptkb:Golgi_apparatus
gptkb:plasma_membrane
|
|
gptkbp:UniProtID
|
gptkb:P01111
|
|
gptkbp:bfsParent
|
gptkb:M-Ras_proteins
gptkb:PF00057
gptkb:small_GTPase_family
gptkb:PF00071
gptkb:GTPase_proteins
|
|
gptkbp:bfsLayer
|
7
|