Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activity |
GTP binding
GTP hydrolysis |
| gptkbp:alsoKnownAs |
gptkb:small_G_protein_family
|
| gptkbp:contains |
gptkb:Arf_family
gptkb:Rab_family gptkb:Ran_family gptkb:Rho_family gptkb:Ras_family |
| gptkbp:example |
gptkb:Ran
gptkb:Rab5 gptkb:RhoA gptkb:HRas gptkb:KRas gptkb:NRas |
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
molecular switch
|
| https://www.w3.org/2000/01/rdf-schema#label |
small GTPase family
|
| gptkbp:molecularWeight |
20-30 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
developmental disorders |
| gptkbp:regulates |
gptkb:GDIs_(guanine_nucleotide_dissociation_inhibitors)
gptkb:GAPs_(GTPase-activating_proteins) gptkb:GEFs_(guanine_nucleotide_exchange_factors) cell differentiation vesicle trafficking cell growth cytoskeletal organization nuclear transport |
| gptkbp:superfamily |
gptkb:Ras_superfamily
|
| gptkbp:bfsParent |
gptkb:RAP2C
gptkb:GTPase_HRas gptkb:RalA gptkb:Ras-GTP |
| gptkbp:bfsLayer |
6
|