|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CMNS
gptkb:N-ras
gptkb:NCMS
gptkb:NRAS1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:discoveredIn
|
1983
|
|
gptkbp:encodes
|
gptkb:NRAS_protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000213281
4893
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
gptkb:neuroblastoma_RAS_viral_oncogene_homolog
|
|
gptkbp:function
|
signal transduction
GTPase activity
|
|
gptkbp:HGNC_ID
|
7989
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NRAS gene
|
|
gptkbp:involvedIn
|
cell differentiation
cell proliferation
apoptosis regulation
|
|
gptkbp:locatedOnChromosome
|
1p13.2
chromosome 1
|
|
gptkbp:memberOf
|
gptkb:RAS_gene_family
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:acute_myeloid_leukemia
colorectal cancer
melanoma
thyroid carcinoma
|
|
gptkbp:OMIM
|
164790
|
|
gptkbp:orthologInMouse
|
gptkb:Nras
|
|
gptkbp:regulates
|
gptkb:MAPK/ERK_pathway
gptkb:PI3K/AKT_pathway
|
|
gptkbp:UniProtID
|
gptkb:P01111
|
|
gptkbp:bfsParent
|
gptkb:Ras_proteins
gptkb:N-ras
gptkb:NRAS_protein
gptkb:RAS_protein
gptkb:RTK-RAS_pathway
gptkb:Ras-GTP
|
|
gptkbp:bfsLayer
|
6
|