P01111

URI: https://gptkb.org/entity/P01111

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog gptkb:Transforming_protein_p21
gptkbp:associatedWith	gptkb:cancer gptkb:Bladder_cancer gptkb:Costello_syndrome gptkb:Gastric_cancer gptkb:Head_and_neck_squamous_cell_carcinoma
gptkbp:biologicalProcess	gptkb:Signal_transduction GTP binding GTPase activity Cell proliferation
gptkbp:cellularComponent	Cytosol Plasma membrane
gptkbp:EC_number	3.6.5.2
gptkbp:Entrez_Gene_ID	gptkb:ENSP00000256078
gptkbp:family	gptkb:Ras_family
gptkbp:firstDescribed	1982
gptkbp:function	gptkb:Signal_transduction GTPase activity
gptkbp:gene	gptkb:HRAS
gptkbp:HGNC_ID	5173
gptkbp:InterPro	gptkb:IPR001806
gptkbp:KEGGID	gptkb:hsa:3265
gptkbp:locatedOnChromosome	11
gptkbp:locusType	gptkb:11p15.5
gptkbp:molecularWeight	21 kDa
gptkbp:OMIM	190020
gptkbp:organism	gptkb:Homo_sapiens
gptkbp:pathway	gptkb:MAPK_signaling_pathway gptkb:PI3K-Akt_signaling_pathway gptkb:Ras_signaling_pathway
gptkbp:PDB	gptkb:5P21 1AA9
gptkbp:postTranslationalModification	Farnesylation Methylation Palmitoylation
gptkbp:protein_name	gptkb:GTPase_HRas
gptkbp:proteinFamily	gptkb:PF00071
gptkbp:Reactome	gptkb:R-HSA-5673001
gptkbp:RefSeq	gptkb:NP_005334.1
gptkbp:reviewedBy	Yes
gptkbp:sequence	189
gptkbp:subcellularLocation	gptkb:Cell_membrane gptkb:Cytoplasm gptkb:Golgi_apparatus
gptkbp:UniProtID	gptkb:P01111
gptkbp:bfsParent	gptkb:NRAS
gptkbp:bfsLayer	5
https://www.w3.org/2000/01/rdf-schema#label	P01111