P01111

URI: https://gptkb.org/entity/P01111
GPTKB entity
Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog
gptkb:Transforming_protein_p21
gptkbp:associatedWith gptkb:cancer
gptkb:Bladder_cancer
gptkb:Costello_syndrome
gptkb:Gastric_cancer
gptkb:Head_and_neck_squamous_cell_carcinoma
gptkbp:biologicalProcess gptkb:Signal_transduction
GTP binding
GTPase activity
Cell proliferation
gptkbp:cellularComponent Cytosol
Plasma membrane
gptkbp:EC_number 3.6.5.2
gptkbp:Entrez_Gene_ID gptkb:ENSP00000256078
gptkbp:family gptkb:Ras_family
gptkbp:firstDescribed 1982
gptkbp:function gptkb:Signal_transduction
GTPase activity
gptkbp:gene gptkb:HRAS
gptkbp:HGNC_ID 5173
https://www.w3.org/2000/01/rdf-schema#label P01111
gptkbp:InterPro gptkb:IPR001806
gptkbp:KEGGID gptkb:hsa:3265
gptkbp:locatedOnChromosome 11
gptkbp:locusType gptkb:11p15.5
gptkbp:molecularWeight 21 kDa
gptkbp:OMIM 190020
gptkbp:organism gptkb:Homo_sapiens
gptkbp:pathway gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:Ras_signaling_pathway
gptkbp:PDB gptkb:5P21
1AA9
gptkbp:postTranslationalModification Farnesylation
Methylation
Palmitoylation
gptkbp:protein_name gptkb:GTPase_HRas
gptkbp:proteinFamily gptkb:PF00071
gptkbp:Reactome gptkb:R-HSA-5673001
gptkbp:RefSeq gptkb:NP_005334.1
gptkbp:reviewedBy Yes
gptkbp:sequence 189
gptkbp:subcellularLocation gptkb:Cell_membrane
gptkb:Cytoplasm
gptkb:Golgi_apparatus
gptkbp:UniProtID gptkb:P01111
gptkbp:bfsParent gptkb:NRAS
gptkbp:bfsLayer 5