|
gptkbp:instanceOf
|
gptkb:protein
gptkb:enzyme
|
|
gptkbp:activatedBy
|
RAF kinases
|
|
gptkbp:alternativeName
|
gptkb:MAPKK2
gptkb:MAP_kinase_kinase_2
gptkb:PRKMK2
CFC4
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:cardio-facio-cutaneous_syndrome
|
|
gptkbp:biologicalProcess
|
protein serine/threonine kinase activity
|
|
gptkbp:EC_number
|
2.7.12.2
|
|
gptkbp:encodedBy
|
gptkb:MAP2K2_gene
|
|
gptkbp:fullName
|
gptkb:Mitogen-activated_protein_kinase_kinase_2
|
|
gptkbp:function
|
phosphorylates and activates ERK1/2
|
|
gptkbp:gene
|
gptkb:MAP2K2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MEK2
|
|
gptkbp:inhibitedBy
|
gptkb:U0126
gptkb:PD0325901
|
|
gptkbp:locatedOnChromosome
|
gptkb:19p13.3
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
gptkb:MAPK/ERK_pathway
|
|
gptkbp:phosphorylates
|
gptkb:ERK1
gptkb:ERK2
|
|
gptkbp:UniProtID
|
P36507
|
|
gptkbp:bfsParent
|
gptkb:BRAF
|
|
gptkbp:bfsLayer
|
5
|