Mitogen-activated protein kinase pathway

URI: https://gptkb.org/entity/Mitogen-activated_protein_kinase_pathway
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf signaling molecule
gptkbp:abbreviation gptkb:MAPK_pathway
gptkbp:activatedBy cytokines
growth factors
environmental stress
gptkbp:alternativeName gptkb:MAPK/ERK_pathway
gptkb:Ras-Raf-MEK-ERK_pathway
gptkb:MAP_kinase_pathway
gptkbp:component gptkb:MEK_(MAPK/ERK_kinase)
gptkb:Raf_kinase
gptkb:ERK_(extracellular_signal-regulated_kinase)
gptkb:JNK_(c-Jun_N-terminal_kinase)
gptkb:p38_MAPK
gptkb:Ras_protein
gptkbp:dysregulationAssociatedWith gptkb:cancer
neurodegenerative diseases
inflammatory diseases
gptkbp:foundIn eukaryotes
https://www.w3.org/2000/01/rdf-schema#label Mitogen-activated protein kinase pathway
gptkbp:involves gptkb:mitogen-activated_protein_kinases
phosphorylation cascade
gptkbp:regulates apoptosis
cell differentiation
cell proliferation
cell survival
gene expression
cellular response to stress
gptkbp:studiedBy cancer research
molecular biology
gptkbp:target kinase inhibitors
gptkbp:bfsParent gptkb:MAPK_signaling_pathway
gptkb:MAP_kinase_pathway
gptkbp:bfsLayer 6