Mitogen-activated protein kinase pathway

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:signaling_molecule
gptkbp:abbreviation	gptkb:MAPK_pathway
gptkbp:activatedBy	cytokines growth factors environmental stress
gptkbp:alternativeName	gptkb:MAPK/ERK_pathway gptkb:Ras-Raf-MEK-ERK_pathway gptkb:MAP_kinase_pathway
gptkbp:component	gptkb:MEK_(MAPK/ERK_kinase) gptkb:Raf_kinase gptkb:ERK_(extracellular_signal-regulated_kinase) gptkb:JNK_(c-Jun_N-terminal_kinase) gptkb:p38_MAPK gptkb:Ras_protein
gptkbp:dysregulationAssociatedWith	gptkb:cancer neurodegenerative diseases inflammatory diseases
gptkbp:foundIn	eukaryotes
gptkbp:involves	gptkb:mitogen-activated_protein_kinases phosphorylation cascade
gptkbp:regulates	apoptosis cell differentiation cell proliferation cell survival gene expression cellular response to stress
gptkbp:studiedBy	cancer research molecular biology
gptkbp:target	kinase inhibitors
gptkbp:bfsParent	gptkb:MAPK_signaling_pathway
gptkbp:bfsLayer	6
https://www.w3.org/2000/01/rdf-schema#label	Mitogen-activated protein kinase pathway