|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:HRAS
gptkb:C-H-RAS
gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog
|
|
gptkbp:alternativeSplicing
|
no
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Costello_syndrome
gptkb:head_and_neck_squamous_cell_carcinoma
bladder cancer
gastric cancer
|
|
gptkbp:discoveredBy
|
gptkb:Harold_E._Varmus
gptkb:J._Michael_Bishop
|
|
gptkbp:encodes
|
gptkb:GTPase_HRas
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000174775
3265
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:function
|
signal transduction
GTP binding
GTPase activity
|
|
gptkbp:HGNC_ID
|
5173
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HRAS1
|
|
gptkbp:interactsWith
|
gptkb:MAP2K1
gptkb:MAPK1
gptkb:RAP1A
gptkb:RASA1
gptkb:RIN1
gptkb:BRAF
gptkb:GRB2
gptkb:PIK3CA
gptkb:RAF1
gptkb:SOS1
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p15.5
chromosome 11
|
|
gptkbp:memberOf
|
gptkb:RAS_gene_family
|
|
gptkbp:mutationAssociatedWith
|
oncogenic transformation
|
|
gptkbp:OMIM
|
190020
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Hras1
Hras
|
|
gptkbp:postTranslationalModification
|
farnesylation
palmitoylation
phosphorylation
|
|
gptkbp:product
|
gptkb:HRas_protein
|
|
gptkbp:regulates
|
cell differentiation
cell proliferation
cell survival
|
|
gptkbp:UniProtID
|
gptkb:P01112
|
|
gptkbp:bfsParent
|
gptkb:HRAS
|
|
gptkbp:bfsLayer
|
5
|