|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:c-Ha-ras
gptkb:HRas1
gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog
gptkb:Transforming_protein_p21
|
|
gptkbp:binds
|
gptkb:GDP
gptkb:GTP
|
|
gptkbp:encodedBy
|
gptkb:HRAS_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000174775
3265
|
|
gptkbp:firstDescribed
|
1982
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
GTPase activity
|
|
gptkbp:HGNC_ID
|
5173
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HRas protein
|
|
gptkbp:interactsWith
|
gptkb:GAPs
gptkb:PI3K
gptkb:GRB2
gptkb:RAF1
gptkb:SOS1
|
|
gptkbp:involvedIn
|
cell differentiation
cell proliferation
cell growth regulation
cell signal transduction
|
|
gptkbp:length
|
189 amino acids
|
|
gptkbp:locatedOn
|
chromosome 11
|
|
gptkbp:memberOf
|
gptkb:Ras_subfamily
|
|
gptkbp:molecularWeight
|
21 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:Costello_syndrome
bladder cancer
head and neck cancer
gastric cancer
|
|
gptkbp:OMIM
|
190020
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
gptkb:5P21
gptkb:1QRA
1AA9
|
|
gptkbp:postTranslationalModification
|
farnesylation
palmitoylation
phosphorylation
|
|
gptkbp:relatedTo
|
gptkb:KRas_protein
gptkb:NRas_protein
|
|
gptkbp:subcellularLocation
|
gptkb:endoplasmic_reticulum
gptkb:Golgi_apparatus
gptkb:plasma_membrane
|
|
gptkbp:UniProtID
|
gptkb:P01112
|
|
gptkbp:bfsParent
|
gptkb:HRAS1
gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog
gptkb:Hras1
gptkb:Transforming_protein_p21
gptkb:transforming_protein_p21
|
|
gptkbp:bfsLayer
|
6
|