head and neck squamous cell carcinoma

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:cancer
gptkb:disease
gptkbp:affects head
neck
gptkbp:associatedWith gptkb:HPV-16
gptkb:Epstein-Barr_virus
gptkbp:canMetastasizeTo lungs
liver
lymph nodes
bones
gptkbp:diagnosedBy imaging
biopsy
gptkbp:hasBiomarker gptkb:EGFR
gptkb:TP53_mutation
gptkb:p16
gptkbp:hasScreeningMethod endoscopy
visual examination
gptkbp:hasStandardOfCare multimodal therapy
https://www.w3.org/2000/01/rdf-schema#label head and neck squamous cell carcinoma
gptkbp:ICD-10_code gptkb:C32
C14
C01-C14
gptkbp:isTreatedAt oncology center
gptkbp:mortalityRate high if advanced
gptkbp:originatedIn mucosal epithelium
gptkbp:prevalence more common in older adults
common in males
gptkbp:prognosis variable
gptkbp:recurrence high in advanced stages
gptkbp:riskFactor alcohol consumption
betel nut chewing
human papillomavirus infection
tobacco use
gptkbp:stageName gptkb:TNM
gptkbp:subjectOf clinical trials
gptkbp:subspecies gptkb:oral_squamous_cell_carcinoma
hypopharyngeal squamous cell carcinoma
laryngeal squamous cell carcinoma
nasopharyngeal squamous cell carcinoma
oropharyngeal squamous cell carcinoma
gptkbp:symptom sore throat
hoarseness
dysphagia
neck mass
gptkbp:treatment surgery
radiation therapy
chemotherapy
immunotherapy
gptkbp:bfsParent gptkb:HRAS
gptkb:Keytruda
gptkbp:bfsLayer 5