|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:IRIS
gptkb:FANCS
gptkb:BRCC1
gptkb:RNF53
gptkb:PSCP
gptkb:PNCA4
|
|
gptkbp:associatedWith
|
gptkb:CHEK2
gptkb:cancer
gptkb:NBN
gptkb:Fanconi_anemia
gptkb:BARD1
gptkb:PALB2
gptkb:FANCA
gptkb:FANCC
gptkb:FANCD2
gptkb:FANCE
gptkb:FANCF
gptkb:FANCG
gptkb:FANCI
gptkb:FANCJ
gptkb:FANCL
gptkb:FANCM
gptkb:FANCN
gptkb:FANCP
gptkb:FANCR
gptkb:FANCS
gptkb:BRCA2
gptkb:RAD51
gptkb:TP53
gptkb:FANCD1
gptkb:FANCO
gptkb:MRE11
gptkb:RAD50
pancreatic cancer
prostate cancer
ATM
|
|
gptkbp:discoveredIn
|
1994
|
|
gptkbp:Entrez_Gene_ID
|
672
ENSG00000012048
|
|
gptkbp:fullName
|
gptkb:BRCA1_DNA_repair_associated
|
|
gptkbp:function
|
tumor suppressor
DNA repair
|
|
gptkbp:gene
|
gptkb:BRCA1
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:1100
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HGNC:1097
|
|
gptkbp:length
|
1863 amino acids
|
|
gptkbp:locatedOnChromosome
|
17
|
|
gptkbp:location
|
gptkb:nucleus
|
|
gptkbp:locusType
|
17q21.31
|
|
gptkbp:mainTerminal
|
gptkb:GO:0003684
gptkb:GO:0006302
gptkb:GO:0008283
GO:0005515
GO:0005634
GO:0000724
GO:0003677
GO:0006281
GO:0006289
GO:0006974
|
|
gptkbp:molecularWeight
|
220 kDa
|
|
gptkbp:OMIM
|
113705
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Brca1
|
|
gptkbp:pathway
|
DNA damage response
homologous recombination
|
|
gptkbp:product
|
gptkb:Breast_cancer_type_1_susceptibility_protein
|
|
gptkbp:proteinFamily
|
gptkb:BRCA_family
|
|
gptkbp:RefSeq
|
gptkb:NM_007294
|
|
gptkbp:UniProtID
|
P38398
|
|
gptkbp:bfsParent
|
gptkb:BRAF
gptkb:BRAF_gene
|
|
gptkbp:bfsLayer
|
5
|