Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
ATLD
MRE11A |
| gptkbp:biologicalProcess |
exonuclease activity
endonuclease activity |
| gptkbp:cellularComponent |
gptkb:nucleus
|
| gptkbp:component |
MRN complex
|
| gptkbp:discoveredBy |
studies in yeast DNA repair
|
| gptkbp:encodes |
MRE11 protein
|
| gptkbp:Entrez_Gene_ID |
ENSG00000125347
|
| gptkbp:expressedIn |
various human tissues
|
| gptkbp:function |
DNA damage response
homologous recombination DNA double-strand break repair |
| gptkbp:gene |
gptkb:MRE11
|
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
HGNC:7230
|
| https://www.w3.org/2000/01/rdf-schema#label |
MRE11
|
| gptkbp:interactsWith |
gptkb:NBS1
gptkb:RAD50 |
| gptkbp:length |
708
|
| gptkbp:locatedOnChromosome |
11q21
|
| gptkbp:mutationAssociatedWith |
cancer susceptibility
Ataxia-telangiectasia-like disorder |
| gptkbp:OMIM |
600814
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Saccharomyces_cerevisiae |
| gptkbp:RefSeq |
NM_005591
|
| gptkbp:UniProtID |
P49959
|
| gptkbp:bfsParent |
gptkb:HGNC:1097
|
| gptkbp:bfsLayer |
6
|