Statements (72)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:associated_with |
gptkb:Oncology
ovarian cancer |
| gptkbp:breeding_behavior |
gptkb:yeast
|
| gptkbp:discovered_by |
1990s
|
| gptkbp:function |
DNA repair
|
| gptkbp:has_role |
meiosis
|
| https://www.w3.org/2000/01/rdf-schema#label |
RAD51
|
| gptkbp:interacts_with |
gptkb:BRCA2
gptkb:BRCA1 |
| gptkbp:involved_in |
homologous recombination
|
| gptkbp:is_essential_for |
cell viability
|
| gptkbp:is_expressed_in |
germ cells
tumor cells |
| gptkbp:is_involved_in |
DNA replication
DNA damage response cell cycle regulation chromosome segregation genome stability genetic recombination telomere maintenance double-strand break repair repair of double-strand breaks repair of interstrand cross-links repair of single-strand breaks repair of DNA breaks repair of DNA cross-linking agents repair of DNA cross-links repair of DNA damage from X-rays repair of DNA damage from biological agents repair of DNA damage from cellular stress repair of DNA damage from chemical agents repair of DNA damage from chemicals repair of DNA damage from chemotherapy repair of DNA damage from cosmic rays repair of DNA damage from endogenous factors repair of DNA damage from environmental factors repair of DNA damage from environmental radiation repair of DNA damage from exogenous factors repair of DNA damage from external agents repair of DNA damage from gamma rays repair of DNA damage from ionizing radiation repair of DNA damage from metabolic processes repair of DNA damage from non-ionizing radiation repair of DNA damage from nuclear radiation repair of DNA damage from oxidative stress repair of DNA damage from physical agents repair of DNA damage from radiation repair of DNA damage from radiation exposure repair of DNA damage from radiation therapy repair of DNA damage from radioactive materials repair of DNA damage from replication errors repair of DNA damage from ultraviolet radiation repair of DNA fragmentation repair of DNA interstrand cross-links repair of DNA lesions repair of DNA mismatches repair of DNA modifications repair of DNA strand breaks repair of UV-induced damage repair of alkylation damage repair of oxidative damage repair of replication stress |
| gptkbp:is_linked_to |
tumorigenesis
|
| gptkbp:is_part_of |
recombination repair pathway
|
| gptkbp:is_regulated_by |
gptkb:RAD52
|
| gptkbp:is_studied_in |
cancer research
|
| gptkbp:is_targeted_at |
chemotherapy drugs
|
| gptkbp:location |
gptkb:Atom
|
| gptkbp:promoter |
gptkb:RAD51_gene
|
| gptkbp:bfsParent |
gptkb:BRCA2
|
| gptkbp:bfsLayer |
5
|