|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
|
|
gptkbp:biologicalProcess
|
DNA binding
ATPase activity
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:encodedBy
|
gptkb:RAD51_gene
|
|
gptkbp:Entrez_Gene_ID
|
5888
|
|
gptkbp:enzymeCommissionNumber
|
3.6.4.12
|
|
gptkbp:expressedIn
|
gptkb:testis
various somatic tissues
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Saccharomyces_cerevisiae
gptkb:Homo_sapiens
|
|
gptkbp:function
|
DNA repair
homologous recombination
|
|
gptkbp:HGNC_ID
|
9820
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RAD51
|
|
gptkbp:interactsWith
|
gptkb:RPA
gptkb:BRCA2
gptkb:RAD52
gptkb:XRCC3
|
|
gptkbp:length
|
339
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_15_(human)
|
|
gptkbp:mutationAssociatedWith
|
genomic instability
cancer predisposition
|
|
gptkbp:OMIM
|
179617
|
|
gptkbp:orthologIn
|
gptkb:RAD51B
gptkb:RAD51C
gptkb:RAD51D
gptkb:RecA_(Escherichia_coli)
gptkb:XRCC2
gptkb:XRCC3
|
|
gptkbp:pathway
|
DNA double-strand break repair
homologous recombination repair pathway
|
|
gptkbp:PDB
|
gptkb:1SZP
|
|
gptkbp:postTranslationalModification
|
phosphorylation
sumoylation
ubiquitination
|
|
gptkbp:regulates
|
gptkb:BRCA1
gptkb:p53
|
|
gptkbp:requires
|
genome stability
meiotic recombination
mitotic recombination
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
nuclear foci
|
|
gptkbp:UniProtID
|
gptkb:Q06609
|
|
gptkbp:bfsParent
|
gptkb:HGNC:1097
gptkb:FANCD2
gptkb:ENSG00000142168
|
|
gptkbp:bfsLayer
|
6
|