|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:actsVia
|
canonical Wnt pathway
non-canonical Wnt pathway
|
|
gptkbp:composedOf
|
gptkb:Wnt_proteins
|
|
gptkbp:discoveredIn
|
1982
|
|
gptkbp:encodedBy
|
gptkb:WNT_genes
|
|
gptkbp:foundIn
|
animals
humans
|
|
gptkbp:hasMember
|
gptkb:Wnt1
gptkb:Wnt11
gptkb:Wnt2
gptkb:Wnt4
gptkb:Wnt6
gptkb:Wnt10A
gptkb:Wnt10B
gptkb:Wnt16
gptkb:Wnt3
gptkb:Wnt5A
gptkb:Wnt5B
gptkb:Wnt7A
gptkb:Wnt7B
gptkb:Wnt8A
gptkb:Wnt8B
gptkb:Wnt9A
gptkb:Wnt9B
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Wnt family
|
|
gptkbp:involvedIn
|
cell proliferation
embryonic development
cell migration
cell signaling
cell fate determination
|
|
gptkbp:modulatedBy
|
gptkb:APC_protein
gptkb:GSK3β
gptkb:R-spondin_proteins
gptkb:TCF/LEF_transcription_factors
gptkb:sFRP_proteins
gptkb:β-catenin
gptkb:DKK1
gptkb:LRP5/6
gptkb:WIF1
gptkb:AXIN
Porcupine enzyme
|
|
gptkbp:namedAfter
|
gptkb:Int-1_gene
gptkb:wingless_gene
|
|
gptkbp:orthologIn
|
gptkb:Drosophila_wingless
gptkb:mouse_Int-1
|
|
gptkbp:recipient
|
gptkb:Frizzled_family_receptors
|
|
gptkbp:relatedTo
|
gptkb:cancer
neurogenesis
bone development
stem cell regulation
|
|
gptkbp:bfsParent
|
gptkb:WNT1_(human)
gptkb:WNT1
gptkb:WNT10A
gptkb:WNT2
gptkb:WNT4
gptkb:WNT7A
|
|
gptkbp:bfsLayer
|
7
|