|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:INT1
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:medulloblastoma
gptkb:bone
osteogenesis imperfecta
developmental processes
oncogenesis
|
|
gptkbp:biologicalProcess
|
cell differentiation
cell proliferation
signaling molecule
neural tube development
pattern specification process
|
|
gptkbp:cellularComponent
|
extracellular region
|
|
gptkbp:discoveredBy
|
gptkb:Harald_Varmus
|
|
gptkbp:encodes
|
gptkb:Wnt-1_protein
|
|
gptkbp:Entrez_Gene_ID
|
7471
ENSG00000125084
|
|
gptkbp:expressedIn
|
brain
embryogenesis
|
|
gptkbp:firstDescribed
|
1982
|
|
gptkbp:function
|
embryonic development
cell signaling
cell fate determination
|
|
gptkbp:geneLocationEnd
|
49121315
|
|
gptkbp:geneLocationStart
|
49115509
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
NM_005430.3
|
|
gptkbp:HGNC_ID
|
12782
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
WNT1
|
|
gptkbp:involvedIn
|
gptkb:Wnt_signaling_pathway
|
|
gptkbp:length
|
370 amino acids
|
|
gptkbp:locatedOnChromosome
|
12q13
|
|
gptkbp:memberOf
|
gptkb:WNT_gene_family
|
|
gptkbp:mutationAssociatedWith
|
nonsense
missense
osteogenesis imperfecta
frameshift
early-onset osteoporosis
|
|
gptkbp:OMIM
|
164820
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInDrosophila
|
wingless
|
|
gptkbp:orthologInMouse
|
gptkb:Wnt1
|
|
gptkbp:orthologInZebrafish
|
wnt1
|
|
gptkbp:pathway
|
Canonical Wnt signaling pathway
Non-canonical Wnt signaling pathway
|
|
gptkbp:proteinFamily
|
gptkb:Wnt_family
Wnt domain
|
|
gptkbp:RefSeq
|
NM_005430
|
|
gptkbp:strand
|
plus
|
|
gptkbp:symbol
|
gptkb:WNT1
|
|
gptkbp:UniProtID
|
P04628
|
|
gptkbp:bfsParent
|
gptkb:WNT
|
|
gptkbp:bfsLayer
|
6
|