|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:INT1
gptkb:Proto-oncogene_Wnt-1
|
|
gptkbp:associatedWith
|
gptkb:cancer
osteogenesis imperfecta
|
|
gptkbp:component
|
extracellular region
|
|
gptkbp:discoveredIn
|
gptkb:mouse
|
|
gptkbp:encodedBy
|
gptkb:WNT1_gene
|
|
gptkbp:Entrez_Gene_ID
|
7471
ENSG00000125084
|
|
gptkbp:expressedIn
|
central nervous system
neural tube
developing midbrain
|
|
gptkbp:firstDescribed
|
1982
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:function
|
embryonic development
cell signaling
Wnt-protein binding
|
|
gptkbp:gene
|
gptkb:WNT1
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GOProcess
|
cell differentiation
canonical Wnt signaling pathway
|
|
gptkbp:HGNC_ID
|
12782
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Wnt1
|
|
gptkbp:involvedIn
|
gptkb:Wnt_signaling_pathway
|
|
gptkbp:length
|
370 amino acids
|
|
gptkbp:locatedOnChromosome
|
12q13.12 (human)
|
|
gptkbp:memberOf
|
gptkb:Wnt_family
|
|
gptkbp:molecularWeight
|
41 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:bone
cancer predisposition
bone fragility
|
|
gptkbp:OMIM
|
164820
|
|
gptkbp:orthologIn
|
gptkb:Drosophila_wingless_(wg)
gptkb:mouse_Wnt1
gptkb:zebrafish_wnt1
|
|
gptkbp:postTranslationalModification
|
palmitoylation
glycosylation
|
|
gptkbp:proteinFamily
|
gptkb:Wnt_proteins
|
|
gptkbp:RefSeq
|
NM_005430
|
|
gptkbp:regulates
|
cell proliferation
cell fate determination
neural development
|
|
gptkbp:relatedTo
|
developmental biology
|
|
gptkbp:signalPeptide
|
present
|
|
gptkbp:subcellularLocation
|
secreted
|
|
gptkbp:UniProtID
|
P04628
|
|
gptkbp:bfsParent
|
gptkb:Wnt_proteins
gptkb:Int-1_(mouse_gene)
gptkb:WNT1
|
|
gptkbp:bfsLayer
|
7
|