Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:RSPO_proteins
|
| gptkbp:binds |
gptkb:LGR4
gptkb:LGR5 gptkb:LGR6 |
| gptkbp:discoveredIn |
2002
|
| gptkbp:domain |
furin-like cysteine-rich domain
thrombospondin type 1 domain |
| gptkbp:encodedBy |
gptkb:RSPO1_gene
gptkb:RSPO2_gene gptkb:RSPO3_gene gptkb:RSPO4_gene |
| gptkbp:foundIn |
vertebrates
|
| gptkbp:function |
potentiate Wnt signaling pathway
|
| gptkbp:involves |
gptkb:cancer
sex determination developmental processes intestinal homeostasis |
| gptkbp:member |
gptkb:RSPO1
gptkb:RSPO2 gptkb:RSPO3 gptkb:RSPO4 |
| gptkbp:regulates |
cell proliferation
stem cell maintenance |
| gptkbp:bfsParent |
gptkb:Wnt_signaling_pathway
|
| gptkbp:bfsLayer |
6
|
| https://www.w3.org/2000/01/rdf-schema#label |
R-spondin proteins
|